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PMID: 18729732 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Review

RNA polymerase elongation factors.

Annual review of microbiology ·Vol. 62 ·2008-00-00 ·Pages 211-33

Roberts JW, Shankar S, Filter JJ

Abstract

The elongation phase of transcription by RNA polymerase is highly regulated and modulated. Both general and operon-specific elongation factors determine the local rate and extent of transcription to coordinate the appearance of transcript with its use as a messenger or functional ribonucleoprotein or regulatory element, as well as to provide operon-specific gene regulation.

MeSH Terms
Bacteria/genetics,metabolism Bacterial Proteins/metabolism Bacteriophage lambda/metabolism Base Sequence DNA-Directed RNA Polymerases/metabolism Escherichia coli/genetics,metabolism Escherichia coli Proteins/metabolism Models, Biological RNA, Bacterial/genetics,metabolism Transcription, Genetic Transcriptional Elongation Factors/metabolism Viral Proteins/metabolism
Chemicals
Bacterial Proteins Escherichia coli Proteins RNA, Bacterial Transcriptional Elongation Factors Viral Proteins DNA-Directed RNA Polymerases
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Roberts Jeffrey W
Department of Molecular Biology and Genetics, Cornell University, Ithaca, New York 14853, USA. jwr7@cornell.edu
Shankar Smita
Filter Joshua J
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Article Info
Journal
Annual review of microbiology
Abbr.
Annu Rev Microbiol
ISSN
0066-4227
DOI
10.1146/annurev.micro.61.080706.093422
Email
jwr7@cornell.edu
Published
2008-00-00
Pages
211-33
Language
English
Region
United States
NLM ID
0372370
PMCID
PMC2819089
Subset
IM
Grants
NIGMS NIH HHS · R01 GM021941 · United States
NIGMS NIH HHS · R01 GM021941-35 · United States
PHS HHS · 21941 · United States
External Links
PubMed source DOI: 10.1146/annurev.micro.61.080706.093422 PMC Full Text View journal details
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