TGFbeta and SMADs talk to NANOG in human embryonic stem cells.
作者:
Jiang(Jianming),Ng(Huck-Hui)
状态:
发布时间2008-08-06
, 更新时间 2016-11-24
期刊:
Cell Stem Cell
摘要:
The TGFbeta/activin signaling pathway is important for the maintenance of human embryonic stem cells. In this issue of Cell Stem Cell, Xu et al. (2008) show that this pathway upregulates the expression of a key pluripotency gene NANOG through SMAD2/3.