Rehabilitation of a contract killer: caspase-3 directs stem cell differentiation.
作者:
Abdul-Ghani(Mohammad),Megeney(Lynn A)
状态:
发布时间2008-06-04
, 更新时间 2016-05-18
期刊:
Cell Stem Cell
摘要:
Activation of caspase-3 is generally acknowledged as a penultimate step in apoptotic cell death pathways. Two studies in this issue of Cell Stem Cell (Fujita et al., 2008; Janzen et al., 2008) provide compelling data to demonstrate that caspase-3 is also a conserved inductive cue for stem cell differentiation.