Cutaneous cancer stem cells: beta-catenin strikes again.
作者:
Braun(Kristin M)
状态:
发布时间2008-05-08
, 更新时间 2016-11-22
期刊:
Cell Stem Cell
摘要:
Cancer stem cells (CSCs) are a subpopulation of tumor cells that retain properties of tissue-specific stem cells, including the ability to self-renew. In a recent article in Nature, Malanchi et al. (2008) identified a population of CD34(+) cells in epidermal tumors that require beta-catenin signaling to maintain a CSC phenotype.