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PMID: 184469 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Neurophysiological defects in temperature-sensitive paralytic mutants of Drosophila melanogaster.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 73 ·No. 9 ·1976-09-00 ·Pages 3253-7

Siddiqi O, Benzer S

Abstract

A new temperature-sensitive paralytic mutant of Drosophila, comatose, is compared behaviorally and physiologically with the previously known types, para and shi. All three have different properties with respect to kinetics of paralysis at high temperature and recovery from paralysis; com is hypersensitive to paralysis by cooling. Neurophysiological experimeents indicate different mechanisms for paralysis in each of the mutants.

MeSH Terms
Animals Drosophila melanogaster/physiology Electric Stimulation Kinetics Larva Membrane Potentials Muscles/physiology Mutation Neuromuscular Junction/physiopathology Paralysis/genetics,physiopathology Synaptic Transmission Temperature
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Siddiqi O
Benzer S
References (10)
10 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
DOI
10.1073/pnas.73.9.3253
Published
1976-09-00
Pages
3253-7
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC430996
Subset
IM
External Links
PubMed source DOI: 10.1073/pnas.73.9.3253 PMC Full Text View journal details
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