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PMID: 184302 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Glycosylation sites of vesicular stomatitis virus glycoprotein.

Journal of virology ·Vol. 19 ·No. 3 ·1976-09-00 ·Pages 871-8

Robertson JS, Etchison JR, Summers DF

Abstract

Detailed analysis on DEAE-Sephadex of the tryptic digestion products of the glycoprotein from vesicular stomatitis virus grown in HeLa suspension cultures revealed the presence of two major and several minor sugar-labeled species. The minor tryptic glycopeptides were converted to one of the two major glycopeptide species by treatment with neuraminidase. Thus, vesicular stomatitis virus glycoprotein contains only two oligosaccharide side chains that are heterogeneous in their sialic acid content.

MeSH Terms

Glycopeptides/analysis Glycoproteins/analysis HeLa Cells Neuraminidase/metabolism Oligosaccharides/analysis Protein Conformation Sialic Acids/analysis Trypsin/metabolism Vesicular stomatitis Indiana virus/analysis Viral Proteins/analysis

Chemicals

Glycopeptides Glycoproteins Oligosaccharides Sialic Acids Viral Proteins Neuraminidase Trypsin

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Robertson J S

Etchison J R

Summers D F

References (15)

15 references, click to expand

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J Virol. 1976 Apr;18(1):167-75 PMID: 176458
The glycoprotein of vesicular stomatitis virus is the antigen that gives rise to and reacts with neutralizing antibody.
J Virol. 1972 Dec;10(6):1231-5 PMID: 4118869
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J Virol. 1970 Aug;6(2):176-82 PMID: 4322870
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J Virol. 1973 Aug;12(2):265-74 PMID: 4355931
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Article Info

Journal

Journal of virology

Abbr.

J Virol

ISSN

0022-538X

DOI

10.1128/JVI.19.3.871-878.1976

Published

1976-09-00

Pages

871-8

Language

English

Region

United States

NLM ID

0113724

PMCID

PMC354927

Subset

External Links

PubMed source DOI: 10.1128/JVI.19.3.871-878.1976 PMC Full Text View journal details

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Glycosylation sites of vesicular stomatitis virus glycoprotein.

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