Predicting fluorouracil toxicity: can we finally do it?

Antimetabolites, Antineoplastic/adverse effects Diarrhea/chemically induced,etiology,genetics Dihydrouracil Dehydrogenase (NADP)/genetics Fluorouracil/adverse effects Genetic Predisposition to Disease Genetic Testing Humans Leucovorin/adverse effects Leukopenia/chemically induced,etiology,genetics Logistic Models Methylenetetrahydrofolate Reductase (NADPH2)/genetics Mucositis/chemically induced,etiology,genetics Odds Ratio Patient Selection Polymorphism, Genetic Predictive Value of Tests Risk Assessment Risk Factors Severity of Illness Index Thymidylate Synthase/genetics Vitamin B Complex/adverse effects

Antimetabolites, Antineoplastic Vitamin B Complex Dihydrouracil Dehydrogenase (NADP) Methylenetetrahydrofolate Reductase (NADPH2) Thymidylate Synthase Leucovorin Fluorouracil