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PMID: 1820688 Published · ppublish English Journal Article Research Support, U.S. Gov't, P.H.S. Review

The DVR gene family in embryonic development.

Trends in genetics : TIG ·Vol. 7 ·No. 11-12 ·1991-00-00 ·Pages 408-12

Lyons KM, Jones CM, Hogan BL

Abstract

The DVR gene family consists of at least 15 members, including decapentaplegic from Drosophila, Xenopus Vg1 and the mammalian bone morphogenetic protein genes, encoding secreted proteins closely related to transforming growth factor beta Genetic and biochemical evidence supports the idea that DVR proteins form part of a cascade of extracellular signalling molecules mediating inductive tissue interactions during development.

Related Genes
BMP-2 BMP-3 BMP-4 BMP-5 BMP-6 BMP-7 DVR DVR-2 DVR-3 DVR-4 DVR-5 DVR-6 DVR-7 OP-1 UbxWnt Vg1 Vgr-1 Wnt-5a dVgr dpp ld
MeSH Terms
Animals Biological Evolution Bone Morphogenetic Protein 3 Bone Morphogenetic Proteins Drosophila Proteins Drosophila melanogaster/embryology,genetics Embryo, Nonmammalian/physiology Embryonic Induction Embryonic and Fetal Development/genetics Gastrula/physiology Gene Expression Regulation Insect Hormones/genetics,physiology Mammals/embryology,genetics Mesoderm Multigene Family Osteogenesis/genetics Proteins/genetics,physiology Signal Transduction Transforming Growth Factor beta/genetics,physiology Xenopus laevis/embryology,genetics
Chemicals
Bone Morphogenetic Protein 3 Bone Morphogenetic Proteins Drosophila Proteins Insect Hormones Proteins Transforming Growth Factor beta dpp protein, Drosophila
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Lyons K M
Department of Cell Biology, Vanderbilt University Medical School, Nashville, TN 37232.
Jones C M
Hogan B L
Article Info
Journal
Trends in genetics : TIG
Abbr.
Trends Genet
ISSN
0168-9525
DOI
10.1016/0168-9525(91)90265-r
Published
1991-00-00
Pages
408-12
Language
English
Region
England
NLM ID
8507085
Subset
IM
External Links
PubMed source DOI: 10.1016/0168-9525(91)90265-r View journal details
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