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PMID: 1807832 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Evolutionarily recent transfer of a group I mitochondrial intron to telomere regions in Saccharomyces cerevisiae.

Current genetics ·Vol. 20 ·No. 5 ·1991-11-00 ·Pages 411-5

Louis EJ, Haber JE

Abstract

The junctions between X and Y' subtelomeric repeats in Saccharomyces cerevisiae usually contain a stretch of telomere sequences, (G1-3T)n. Two of three cloned X-Y' junctions from strain YP1 have a replacement of about 200 bp of X, the internal telomere sequence, and 49 bp of Y' by a 292 bp sequence. The first 227 bp of this insertion sequence are 100% identical to the fourth intron of cytochrome b. The rest of the insertion has homology to an unknown dispersed nuclear sequence. Recombination among subtelomeric regions can explain the nuclear distribution of this sequence and why telomeres can trap and maintain sequences that would otherwise be lost.

MeSH Terms
Base Sequence Biological Evolution DNA, Fungal Introns Mitochondria Molecular Sequence Data Recombination, Genetic Saccharomyces cerevisiae/genetics,ultrastructure Telomere
Chemicals
DNA, Fungal
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Louis E J
Rosenstiel Center, Brandeis University, Waltham, MA 02254-9110.
Haber J E
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Article Info
Journal
Current genetics
Abbr.
Curr Genet
ISSN
0172-8083
DOI
10.1007/BF00317070
Published
1991-11-00
Pages
411-5
Language
English
Region
United States
NLM ID
8004904
Subset
IM
Grants
NCRR NIH HHS · RR04671 · United States
Databases
GENBANK
M58718, M63935, M63936, M63937, M63938, S39727, S39777, S60919, S60920, X62800
External Links
PubMed source DOI: 10.1007/BF00317070 View journal details
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