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PMID: 18005677 Published · ppublish English Journal Article Research Support, N.I.H., Extramural Research Support, Non-U.S. Gov't Comment

Viral evasion of autophagy.

Cell host & microbe ·Vol. 1 ·No. 1 ·2007-03-15 ·Pages 9-11

Münz C

Abstract

Restriction of both bacterial and viral pathogen growth by autophagy has been documented in vitro. In this issue of Cell Host & Microbe, Orvedahl et al. demonstrate for the first time that inhibition of autophagy by a viral gene product is essential for neurovirulence of herpesviruses.

MeSH Terms

Antigen Presentation Apoptosis Regulatory Proteins/metabolism Autophagy Beclin-1 Biological Evolution Humans Immune System/physiology Membrane Proteins/metabolism RNA Viruses/genetics,pathogenicity Viral Proteins/genetics,metabolism

Chemicals

Apoptosis Regulatory Proteins BECN1 protein, human Beclin-1 Membrane Proteins Viral Proteins

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Münz Christian

Laboratory of Viral Immunobiology, The Rockefeller University, 1230 York Avenue, New York, NY 10021, USA. munzc@rockefeller.edu

Article Info

Journal

Cell host & microbe

Abbr.

Cell Host Microbe

ISSN

1934-6069

DOI

10.1016/j.chom.2007.02.005

munzc@rockefeller.edu

Published

2007-03-15

Pages

9-11

Language

English

Region

United States

NLM ID

101302316

Subset

Grants

PHS HHS · DAIDS-BAA-06-19 · United States

NCI NIH HHS · R01CA101741 · United States

NCI NIH HHS · R01CA108609 · United States

Corrections

CommentOn

PMID: 18005679

External Links

PubMed source DOI: 10.1016/j.chom.2007.02.005 View journal details

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Viral evasion of autophagy.

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