Structural basis for the specificity of antibody-antigen reactions and structural mechanisms for the diversification of antigen-binding specificities.

Amino Acid Sequence Animals Antibodies/analysis Antibody Specificity Antigen-Antibody Reactions Binding Sites, Antibody Humans Immunoglobulin Fragments/analysis Immunoglobulin Heavy Chains Immunoglobulin Light Chains Immunoglobulins/analysis Molecular Conformation Phosphorylcholine/immunology Polysaccharides, Bacterial/immunology Protein Conformation Streptococcus pneumoniae Structure-Activity Relationship

Antibodies Immunoglobulin Fragments Immunoglobulin Heavy Chains Immunoglobulin Light Chains Immunoglobulins Polysaccharides, Bacterial Phosphorylcholine