Adenosine 3',5'-monophosphate-dependent protein kinase from brain.

Science (New York, N.Y.) ·Vol. 165 ·No. 3888 ·1969-07-04 ·Pages 63-5

Miyamoto E, Kuo JF, Greengard P

Abstract

Adenosine 3',5'-monophosphate at a concentration of 5 x 10(-7) mole per liter causes a 400 percent increase in the rate of phosphorylation of histone catalyzed by a partially purified enzyme preparation from rabbit brain. The data provide the first direct evidence of a biochemical action of adenosine 3',5'-monophosphate in the brain.

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Miyamoto E

Kuo J F

Greengard P

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.165.3888.63

Published

1969-07-04

Pages

63-5

Language

English

Region

United States

NLM ID

0404511

External Links

PubMed source DOI: 10.1126/science.165.3888.63 View journal details

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