Microdetermination of Calcium by Aequorin Luminescence.

Science (New York, N.Y.) ·Vol. 140 ·No. 3573 ·1963-06-21 ·Pages 1339-40

Shimomura O, Johnson FH, Saiga Y

Abstract

A bioluminescent protein, aequorin, isolated from the jellyfish Aequorea in dilute disodium ethylenediaminetetraacetate solution, emits light on addition specifically of Ca(++) or Sr(++), thus providing the basis for a simple, quantitative micromethod for the determination of these cations, especially in biological fluids.

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Shimomura O

Johnson F H

Saiga Y

Article Info

Journal

Science (New York, N.Y.)

Abbr.

Science

ISSN

0036-8075

DOI

10.1126/science.140.3573.1339

Published

1963-06-21

Pages

1339-40

Language

English

Region

United States

NLM ID

0404511

External Links

PubMed source DOI: 10.1126/science.140.3573.1339 View journal details

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