New fashions in vesicle coats.

Clathrin-coated vesicles are responsible for the sorting transport of membrane proteins within cells. Their co of the self-assembling protein clathrin, and adaptor r. interact with the vesicle cargo and localize clathrin tc Recently, novel clathrin-like and adaptor-like proteins identified. Here, Frances Brodsky discusses various in these findings, including the possibility that the novel expanded functions beyond the conventional roles of the in coated-vesicle formation. In this context, the mech which coats influence vesicle formation is reconsidere.