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PMID: 17630276 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S.

Multilevel interactions between ethylene and auxin in Arabidopsis roots.

The Plant cell ·Vol. 19 ·No. 7 ·2007-07-00 ·Pages 2169-85

Stepanova AN, Yun J, Likhacheva AV, Alonso JM

Abstract

Hormones play a central role in the coordination of internal developmental processes with environmental signals. Herein, a combination of physiological, genetic, cellular, and whole-genome expression profiling approaches has been employed to investigate the mechanisms of interaction between two key plant hormones: ethylene and auxin. Quantification of the morphological effects of ethylene and auxin in a variety of mutant backgrounds indicates that auxin biosynthesis, transport, signaling, and response are required for the ethylene-induced growth inhibition in roots but not in hypocotyls of dark-grown seedlings. Analysis of the activation of early auxin and ethylene responses at the cellular level, as well as of global changes in gene expression in the wild type versus auxin and ethylene mutants, suggests a simple mechanistic model for the interaction between these two hormones in roots, according to which ethylene and auxin can reciprocally regulate each other's biosyntheses, influence each other's response pathways, and/or act independently on the same target genes. This model not only implies existence of several levels of interaction but also provides a likely explanation for the strong ethylene response defects observed in auxin mutants.

MeSH Terms
Arabidopsis/drug effects,genetics,metabolism Arabidopsis Proteins/metabolism Binding Sites DNA-Binding Proteins/metabolism Ethylenes/metabolism,pharmacology Gene Expression Profiling Genes, Plant Genes, Reporter Glucuronidase/metabolism Indoleacetic Acids/metabolism Models, Biological Mutation/genetics Nuclear Proteins/metabolism Oligonucleotide Array Sequence Analysis Plant Roots/drug effects,enzymology,growth & development,metabolism Promoter Regions, Genetic/genetics Reverse Transcriptase Polymerase Chain Reaction Transcription Factors/metabolism
Chemicals
ARF1 protein, Arabidopsis Arabidopsis Proteins DNA-Binding Proteins EIN3 protein, Arabidopsis Ethylenes Indoleacetic Acids Nuclear Proteins Transcription Factors ethylene Glucuronidase
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Stepanova Anna N
Department of Genetics, North Carolina State University, Raleigh, North Carolina 27695, USA.
Yun Jeonga
Likhacheva Alla V
Alonso Jose M
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Article Info
Journal
The Plant cell
Abbr.
Plant Cell
ISSN
1040-4651
DOI
10.1105/tpc.107.052068
Published
2007-07-00
Epub
2007-00-13
Pages
2169-85
Language
English
Region
England
NLM ID
9208688
PMCID
PMC1955696
Subset
IM
Databases
GEO
GSE7432
External Links
PubMed source DOI: 10.1105/tpc.107.052068 PMC Full Text View journal details
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