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PMID: 1763012 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Chemical implementation of neural networks and Turing machines.

Hjelmfelt A, Weinberger ED, Ross J

Abstract

We propose a reversible reaction mechanism with a single stationary state in which certain concentrations assume either high or low values dependent on the concentration of a catalyst. The properties of this mechanism are those of a McCulloch-Pitts neuron. We suggest a mechanism of interneuronal connections in which the stationary state of a chemical neuron is determined by the state of other neurons in a homogeneous chemical system and is thus a "hardware" chemical implementation of neural networks. Specific connections are determined for the construction of logic gates: AND, NOR, etc. Neural networks may be constructed in which the flow of time is continuous and computations are achieved by the attainment of a stationary state of the entire chemical reaction system, or in which the flow of time is discretized by an oscillatory reaction. In another article, we will give a chemical implementation of finite state machines and stack memories, with which in principle the construction of a universal Turing machine is possible.

MeSH Terms
Animals Mathematics Memory Models, Chemical Models, Neurological Neural Networks, Computer Neurons/physiology
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Hjelmfelt A
Max-Planck-Institut für Biophysikalische Chemie, Göttingen, Federal Republic of Germany.
Weinberger E D
Ross J
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10 references, click to expand
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Article Info
Journal
Proceedings of the National Academy of Sciences of the United States of America
Abbr.
Proc Natl Acad Sci U S A
ISSN
0027-8424
Published
1991-12-15
Pages
10983-7
Language
English
Region
United States
NLM ID
7505876
PMCID
PMC53057
Subset
IM
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