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PMID: 17586828 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

beadarray: R classes and methods for Illumina bead-based data.

Bioinformatics (Oxford, England) ·Vol. 23 ·No. 16 ·2007-08-15 ·Pages 2183-4

Dunning MJ, Smith ML, Ritchie ME, Tavaré S

Abstract

The R/Bioconductor package beadarray allows raw data from Illumina experiments to be read and stored in convenient R classes. Users are free to choose between various methods of image processing, background correction and normalization in their analysis rather than using the defaults in Illumina's; proprietary software. The package also allows quality assessment to be carried out on the raw data. The data can then be summarized and stored in a format which can be used by other R/Bioconductor packages to perform downstream analyses. Summarized data processed by Illumina's; BeadStudio software can also be read and analysed in the same manner. The beadarray package is available from the Bioconductor web page at www.bioconductor.org. A user's guide and example data sets are provided with the package.

MeSH Terms
Algorithms Databases, Genetic Image Interpretation, Computer-Assisted/methods In Situ Hybridization, Fluorescence/methods Microspheres Oligonucleotide Array Sequence Analysis/methods Programming Languages Sequence Analysis, DNA/methods Software
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
Dunning Mark J
Department of Oncology, University of Cambridge, CRUK Cambridge Research Institute, Li Ka Shing Centre, Robinson Way, Cambridge, CB2 0RE, UK. md392@cam.ac.uk
Smith Mike L
Ritchie Matthew E
Tavaré Simon
Article Info
Journal
Bioinformatics (Oxford, England)
Abbr.
Bioinformatics
ISSN
1367-4811
Published
2007-08-15
Epub
2007-00-22
Pages
2183-4
Language
English
Region
England
NLM ID
9808944
Subset
IM
Analysis Services
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