Synergism between NF-kappa B1/p50 and Notch2 during the development of marginal zone B lymphocytes.

Agammaglobulinaemia Tyrosine Kinase Animals B-Lymphocyte Subsets/enzymology,immunology,metabolism,pathology Basic Helix-Loop-Helix Transcription Factors/biosynthesis,genetics Cell Communication/genetics,immunology Cell Differentiation/genetics,immunology DNA-Binding Proteins/biosynthesis,genetics Enzyme Activation/immunology Gene Expression Regulation/immunology Mice Mice, Inbred C57BL Mice, Inbred CBA Mice, Knockout NF-kappa B p50 Subunit/deficiency,genetics,physiology Protein-Tyrosine Kinases/metabolism Receptor, Notch2/physiology Repressor Proteins/biosynthesis,genetics Signal Transduction/immunology Spleen/immunology,metabolism,pathology Ubiquitin-Protein Ligases

Basic Helix-Loop-Helix Transcription Factors DNA-Binding Proteins Hes5 protein, mouse NF-kappa B p50 Subunit Notch2 protein, mouse Receptor, Notch2 Repressor Proteins Dtx1 protein, mouse Ubiquitin-Protein Ligases Protein-Tyrosine Kinases Agammaglobulinaemia Tyrosine Kinase