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题目:: Planar polarity and tissue morphogenesis.
作者:: Zallen(Jennifer A)
状态:: 发布时间2007-06-18 , 更新时间 2007-06-18
期刊:: Cell
摘要:: Planar polarity is a global, tissue-level phenomenon that coordinates cell behavior in a two-dimensional plane. The Frizzled/planar cell polarity (PCP) and anterior-posterior (AP) patterning systems for planar polarity operate in a variety of cell types and provide direction to cells with different morphologies and behaviors. These two systems involve different sets of proteins but both use directional cues provided locally by communication between neighboring cells. This review describes our current understanding of the mechanisms that transmit directional signals from cell to cell and compares the strategies for generating global systems of spatial information in stationary and dynamic cell populations.
语言:: eng
DOI:: 10.1016/j.cell.2007.05.050

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