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PMID: 1755984 Published · ppublish English Journal Article Review

Protein tumor antigens.

Current opinion in immunology ·Vol. 3 ·No. 5 ·1991-10-00 ·Pages 654-8

Srivastava PK

Abstract

Immunogenic tumor antigens have been sought through a variety of paradigms for several past decades. Recent developments in antigen presentation have radically changed the prism through which we view these enigmatic antigens. This article discusses the small but growing treasure chest of these antigens--stress-induced proteins, the P1AB antigen of the P815 mastocytoma, the p53 tumor suppressor protein, the gp95/p97 antigen of human melanoma, mucins and others.

Related Genes
tum
MeSH Terms
Animals Antibodies, Neoplasm/analysis Antigens, Neoplasm/genetics,immunology Gene Expression Regulation, Neoplastic Heat-Shock Proteins/immunology Humans Immunity, Cellular Mast-Cell Sarcoma/immunology Mice Neoplasm Proteins/genetics,immunology Neoplasm Transplantation Neoplasms/immunology T-Lymphocytes/immunology Transplantation, Heterologous Tumor Suppressor Protein p53/immunology
Chemicals
Antibodies, Neoplasm Antigens, Neoplasm Heat-Shock Proteins Neoplasm Proteins Tumor Suppressor Protein p53
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Srivastava P K
Mount Sinai School of Medicine, New York.
Article Info
Journal
Current opinion in immunology
Abbr.
Curr Opin Immunol
ISSN
0952-7915
Published
1991-10-00
Pages
654-8
Language
English
Region
England
NLM ID
8900118
Subset
IM
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