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PMID: 17455176 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Molecular basis for trehalase inhibition revealed by the structure of trehalase in complex with potent inhibitors.

Angewandte Chemie (International ed. in English) ·Vol. 46 ·No. 22 ·2007-00-00 ·Pages 4115-9

Gibson RP, Gloster TM, Roberts S, Warren RA, Storch de Gracia I, García A, Chiara JL, Davies GJ

Abstract

暂无摘要

MeSH Terms
Catalysis Colorimetry Disaccharides/antagonists & inhibitors,chemistry Enzyme Inhibitors/pharmacology Hydrogen Bonding Inositol/analogs & derivatives,antagonists & inhibitors,chemistry Protein Conformation Trehalase/antagonists & inhibitors,chemistry
Chemicals
Disaccharides Enzyme Inhibitors trehazolin validamycin A Inositol Trehalase
Authors & Affiliations
8 authors, click to expand affiliations / ORCID
Gibson Robert P
Department of Chemistry, York Structural Biology Laboratory, York, YO, UK.
Gloster Tracey M
Roberts Shirley
Warren R Anthony J
Storch de Gracia Isabel
García Angela
Chiara Jose L
Davies Gideon J
Article Info
Journal
Angewandte Chemie (International ed. in English)
Abbr.
Angew Chem Int Ed Engl
ISSN
1433-7851
DOI
10.1002/anie.200604825
Published
2007-00-00
Pages
4115-9
Language
English
Region
Germany
NLM ID
0370543
Subset
IM
Grants
Biotechnology and Biological Sciences Research Council · B20376 · United Kingdom
External Links
PubMed source DOI: 10.1002/anie.200604825 View journal details
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