Home LiteratureArticle Details

PMID: 17420929 Published · ppublish English Letter Research Support, Non-U.S. Gov't

IL2RA/CD25 polymorphisms contribute to multiple sclerosis susceptibility.

Journal of neurology ·Vol. 254 ·No. 5 ·2007-05-00 ·Pages 682-4

Matesanz F, Caro-Maldonado A, Fedetz M, Fernández O, Milne RL, Guerrero M, Delgado C, Alcina A

Abstract

暂无摘要

MeSH Terms

Case-Control Studies Chi-Square Distribution DNA Mutational Analysis Female Gene Frequency Genetic Predisposition to Disease Genotype Humans Interleukin-2 Receptor alpha Subunit/genetics Male Multiple Sclerosis/epidemiology,genetics Odds Ratio Polymorphism, Genetic/genetics Rhodamines/metabolism Spain/epidemiology Whites/genetics

Chemicals

IL2RA protein, human Interleukin-2 Receptor alpha Subunit Rhodamines Texas Red-X succinimidyl ester

Authors & Affiliations

8 authors, click to expand affiliations / ORCID

Matesanz Fuencisla

Caro-Maldonado Alfredo

Fedetz Maria

Fernández Oscar

Milne Roger L

Guerrero Miguel

Delgado Concepción

Alcina Antonio

References (17)

17 references, click to expand

Evidence for a type 1 diabetes susceptibility locus (IDDM10) on human chromosome 10p11-q11.
Hum Mol Genet. 1997 Jul;6(7):1011-6 PMID: 9215668
DQB1*0602 allele shows a strong association with multiple sclerosis in patients in Malaga, Spain.
J Neurol. 2004 Apr;251(4):440-4 PMID: 15083289
The basis for IL-2-induced IL-2 receptor alpha chain gene regulation: importance of two widely separated IL-2 response elements.
Immunity. 2001 Jul;15(1):159-72 PMID: 11485747
Evidence for pathogenic heterogeneity in multiple sclerosis.
Ann Neurol. 2004 Aug;56(2):308 PMID: 15293289
Genetics of multiple sclerosis: linkage and association studies.
Am J Pharmacogenomics. 2002;2(1):37-58 PMID: 12083953
The epidemiology of multiple sclerosis.
Mayo Clin Proc. 1997 Sep;72(9):871-8 PMID: 9294536
Localization of the fourth locus (GLC1E) for adult-onset primary open-angle glaucoma to the 10p15-p14 region.
Am J Hum Genet. 1998 Mar;62(3):641-52 PMID: 9497264
Natural recovery and protection from autoimmune encephalomyelitis: contribution of CD4+CD25+ regulatory cells within the central nervous system.
J Immunol. 2005 Sep 1;175(5):3025-32 PMID: 16116190
Allelic expression and interleukin-2 polymorphisms in multiple sclerosis.
J Neuroimmunol. 2001 Sep 3;119(1):101-5 PMID: 11525806
Human immune disorder arising from mutation of the alpha chain of the interleukin-2 receptor.
Proc Natl Acad Sci U S A. 1997 Apr 1;94(7):3168-71 PMID: 9096364
Novel CD28-responsive enhancer activated by CREB/ATF and AP-1 families in the human interleukin-2 receptor alpha-chain locus.
Mol Cell Biol. 2001 Jul;21(14):4515-27 PMID: 11416131
Effects of the multiple sclerosis associated -330 promoter polymorphism in IL2 allelic expression.
J Neuroimmunol. 2004 Mar;148(1-2):212-7 PMID: 14975604
New diagnostic criteria for multiple sclerosis: guidelines for research protocols.
Ann Neurol. 1983 Mar;13(3):227-31 PMID: 6847134
Refining the linkage analysis on chromosome 10 in 449 sib-pairs with multiple sclerosis.
J Neuroimmunol. 2003 Oct;143(1-2):31-8 PMID: 14575911
Identifying disease modifying genes in multiple sclerosis.
J Neuroimmunol. 2002 Feb;123(1-2):144-59 PMID: 11880159
Tolerance, not immunity, crucially depends on IL-2.
Nat Rev Immunol. 2004 Sep;4(9):665-74 PMID: 15343366
Localization of a type 1 diabetes locus in the IL2RA/CD25 region by use of tag single-nucleotide polymorphisms.
Am J Hum Genet. 2005 May;76(5):773-9 PMID: 15776395

Article Info

Journal

Journal of neurology

Abbr.

J Neurol

ISSN

0340-5354

DOI

10.1007/s00415-006-0416-4

Published

2007-05-00

Epub

2007-00-10

Pages

682-4

Language

English

Region

Germany

NLM ID

0423161

Subset

External Links

PubMed source DOI: 10.1007/s00415-006-0416-4 View journal details

Analysis Services

IL2RA/CD25 polymorphisms contribute to multiple sclerosis susceptibility.

Contact

WeChat Official Account