Membrane trafficking: three steps to fusion.

Current biology : CB ·Vol. 17 ·No. 7 ·2007-04-03 ·Pages R255-8

Burgoyne RD, Morgan A

Abstract

Membrane fusion involves the action of members of the SNARE protein family as well as Sec1/Munc18 (SM) proteins, which have been found to interact with SNAREs in three distinct ways. Recent work has established that Munc18-1 directly stimulates fusion and possibly uses all three modes of SNARE interaction.

MeSH Terms

Animals Membrane Fusion Membranes/metabolism Models, Molecular Munc18 Proteins/metabolism SNARE Proteins/metabolism Yeasts/metabolism

Chemicals

Munc18 Proteins SNARE Proteins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Burgoyne Robert D

The Physiological Laboratory, School of Biomedical Sciences, University of Liverpool, Crown Street, Liverpool, UK. burgoyne@liverpool.ac.uk

Morgan Alan

Article Info

Journal

Current biology : CB

Abbr.

Curr Biol

ISSN

0960-9822

DOI

10.1016/j.cub.2007.02.006

burgoyne@liverpool.ac.uk

Published

2007-04-03

Pages

R255-8

Language

English

Region

England

NLM ID

9107782

Subset

External Links

PubMed source DOI: 10.1016/j.cub.2007.02.006 View journal details

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