Home LiteratureArticle Details
PMID: 17376388 Published · ppublish English Comment Journal Article

Division of labor: specialization of sphingosine kinases in mast cells.

Immunity ·Vol. 26 ·No. 3 ·2007-03-00 ·Pages 271-3

Beaven MA

Abstract

Generation of sphingosine-1-phosphate by sphingosine kinases (SphKs) promotes allergic inflammatory diseases, but the roles of the individual SphK isoforms are unclear. Olivera et al. (2007) show that SphK2 regulates mast cell activation whereas SphK1 enhances susceptibility to antigen challenge in vivo.

MeSH Terms
Animals Antigens/immunology Humans Hypersensitivity, Immediate/enzymology,immunology Mast Cells/enzymology,immunology Mice Phosphotransferases (Alcohol Group Acceptor)/physiology
Chemicals
Antigens Phosphotransferases (Alcohol Group Acceptor) sphingosine kinase
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Beaven Michael A
National Heart, Lung, and Blood Institute, National Institutes of Health, Room 8N109/Bldg. 10, Bethesda, MD 20892, USA. beavenm@nhlbi.nih.gov
Article Info
Journal
Immunity
Abbr.
Immunity
ISSN
1074-7613
DOI
10.1016/j.immuni.2007.03.002
Email
beavenm@nhlbi.nih.gov
Published
2007-03-00
Pages
271-3
Language
English
Region
United States
NLM ID
9432918
Subset
IM
Corrections
CommentOn
PMID: 17346996
External Links
PubMed source DOI: 10.1016/j.immuni.2007.03.002 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2