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PMID: 17353114 Published · ppublish English Journal Article Review

The role of antibiotics in asthma.

International journal of antimicrobial agents ·Vol. 29 ·No. 5 ·2007-05-00 ·Pages 485-93

Blasi F, Johnston SL

Abstract

There is increasing evidence that atypical respiratory pathogens such as Chlamydophila pneumoniae and Mycoplasma pneumoniae may contribute to the pathogenesis of both stable asthma and asthma exacerbations. It is postulated that these organisms may contribute to inflammation in the airways possibly by activating inflammatory mechanisms in the respiratory tract. The macrolide class of antibiotics may have a part to play in the management of asthma by exerting anti-inflammatory effects on the chronically inflamed airways in addition to their anti-infective action. The ketolide antibiotics may also have similar properties. This paper discusses the role of these antibiotics in the management of asthma.

MeSH Terms
Anti-Bacterial Agents/therapeutic use Asthma/drug therapy,etiology,microbiology Child Clinical Trials as Topic Humans Respiratory Tract Infections/complications,microbiology
Chemicals
Anti-Bacterial Agents
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Blasi Francesco
Institute of Respiratory Diseases, University of Milan, IRCCS Ospedale Maggiore Policlinico, Mangiagalli e Regina Elena, Milan, Italy.
Johnston Sebastian L
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Article Info
Journal
International journal of antimicrobial agents
Abbr.
Int J Antimicrob Agents
ISSN
0924-8579
DOI
10.1016/j.ijantimicag.2006.11.029
Published
2007-05-00
Epub
2007-00-13
Pages
485-93
Language
English
Region
Netherlands
NLM ID
9111860
PMCID
PMC7126415
Subset
IM
External Links
PubMed source DOI: 10.1016/j.ijantimicag.2006.11.029 PMC Full Text View journal details
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