Home LiteratureArticle Details
PMID: 1729256 Published · ppublish English Editorial Review

Immunoscintigraphy for cancer detection: "a thousand ills require a thousand cures".

Journal of cancer research and clinical oncology ·Vol. 118 ·No. 1 ·1992-00-00 ·Pages 1-15

de Bie SH, Ferreira TC, Pauwels EK, Cleton FJ

Abstract

暂无摘要

MeSH Terms
Animals Humans Neoplasms/diagnostic imaging Radioimmunodetection/methods
Authors & Affiliations
4 authors, click to expand affiliations / ORCID
de Bie S H
Ferreira T C
Pauwels E K
Cleton F J
References (118)
118 references, click to expand
  1. Liposomally entrapped second antibody improves tumour imaging with radiolabelled (first) antitumour antibody.
    Lancet. 1982 Oct 2;2(8301):739-42 PMID: 6125812
  2. Limitations to the killing of tumours using radiolabelled antibodies.
    Br J Radiol. 1987 Jun;60(714):567-72 PMID: 3620814
  3. Differences in biodistribution of indium-111-and iodine-131-labeled B72.3 monoclonal antibodies in patients with colorectal cancer.
    J Nucl Med. 1989 Mar;30(3):320-7 PMID: 2738661
  4. Comparative tumour localization properties of radiolabelled monoclonal antibody preparations of defined immunoreactivities.
    Eur J Nucl Med. 1987;13(7):348-52 PMID: 3428284
  5. Population kinetics of carcinoma cells, capillary endothelial cells, and fibroblasts in a transplanted mouse mammary tumor.
    Cancer Res. 1970 Oct;30(10):2470-6 PMID: 4097429
  6. Stability, characterization, and kinetics of 111In-labeled monoclonal antitumor antibodies in normal animals and nude mouse-human tumor models.
    Cancer Res. 1983 Nov;43(11):5347-55 PMID: 6616469
  7. Radioimmunodetection of cutaneous T-cell lymphoma with 111In-labeled T101 monoclonal antibody.
    N Engl J Med. 1986 Sep 11;315(11):673-80 PMID: 3489185
  8. Dual isotope study of iodine-125 and indium-111-labeled antibody in athymic mice.
    J Nucl Med. 1989 Mar;30(3):374-84 PMID: 2738666
  9. Tumor localization of radiolabeled antibodies against carcinoembryonic antigen in patients with carcinoma: a critical evaluation.
    N Engl J Med. 1980 Jul 3;303(1):5-10 PMID: 7189578
  10. Continuous cultures of fused cells secreting antibody of predefined specificity.
    Nature. 1975 Aug 7;256(5517):495-7 PMID: 1172191
  11. Quo vadis radioimmune imaging.
    J Nucl Med. 1989 Nov;30(11):1911-5 PMID: 2681570
  12. Immune-complex-mediated biologic effects.
    N Engl J Med. 1981 Feb 26;304(9):518-20 PMID: 6450327
  13. Immunospecific saturable clearance mechanisms for indium-111-labeled anti-melanoma monoclonal antibody 96.5 in humans.
    Cancer Res. 1988 Aug 1;48(15):4417-22 PMID: 3390837
  14. Radioactive labeling of antibody: a simple and efficient method.
    Science. 1983 May 6;220(4597):613-5 PMID: 6836304
  15. Improved radioimaging and tumor localization with monoclonal F(ab')2.
    J Nucl Med. 1983 Apr;24(4):316-25 PMID: 6339689
  16. Detection of colorectal carcinoma by emission-computerized tomography after injection of 123I-labeled Fab or F(ab')2 fragments from monoclonal anti-carcinoembryonic antigen antibodies.
    J Clin Invest. 1986 Jan;77(1):301-11 PMID: 3484753
  17. Reduction of background activities by introduction of a diester linkage between antibody and a chelate in radioimmunodetection of tumor.
    J Nucl Med. 1989 Oct;30(10):1693-701 PMID: 2795209
  18. Experimental studies of radioimmunodetection of cancer: an overview.
    Cancer Res. 1990 Feb 1;50(3 Suppl):809s-813s PMID: 2404581
  19. Pharmacokinetics of 111In-labeled anti-p97 monoclonal antibody in patients with metastatic malignant melanoma.
    Cancer Res. 1985 May;45(5):2382-6 PMID: 3986780
  20. Imaging of melanoma with L-131-labeled monoclonal antibodies.
    J Nucl Med. 1983 Feb;24(2):123-9 PMID: 6822875
  21. Problems associated with radioimmunodetection and possibilities for future solutions.
    J Biol Response Mod. 1987 Jun;6(3):235-62 PMID: 3298553
  22. Experimental studies of tumor radioimmunodetection using antibody mixtures against carcinoembryonic antigen (CEA) and colon-specific antigen-p (CSAp).
    Int J Cancer. 1981 Jan 15;27(1):101-5 PMID: 7251228
  23. Immunoscintigraphy of colon carcinoma.
    J Nucl Med. 1984 Mar;25(3):307-14 PMID: 6366160
  24. The use of paired labeling in the determination of tumor-localizing antibodies.
    Cancer Res. 1957 Oct;17(9):845-50 PMID: 13472674
  25. 99Tcm-labelled anti-CEA monoclonal antibody for tumour immunoscintigraphy: first clinical results.
    Nucl Med Commun. 1989 May;10(5):345-52 PMID: 2662074
  26. Determinants of tumor blood flow: a review.
    Cancer Res. 1988 May 15;48(10):2641-58 PMID: 3282647
  27. Kinetic model for the biodistribution of an 111In-labeled monoclonal antibody in humans.
    Cancer Res. 1987 Jun 15;47(12):3328-36 PMID: 3581071
  28. Pharmacokinetics of an indium-111-labeled monoclonal antibody in cancer patients.
    J Nucl Med. 1985 Aug;26(8):849-58 PMID: 3861793
  29. Capillary permeability of two transplantable rat tumours as compared with various normal organs of the rat.
    Bibl Anat. 1973;12:511-8 PMID: 4790386
  30. Immunoreactivity affects the biodistribution and tumor targeting of radiolabeled anti-P97 Fab fragment.
    J Nucl Med. 1990 Feb;31(2):202-10 PMID: 2313360
  31. Improving the tumor retention of radioiodinated antibody: aryl carbohydrate adducts.
    Cancer Res. 1990 Feb 1;50(3 Suppl):783s-788s PMID: 2297724
  32. Monoclonal antibody imaging of human melanoma. Radioimmunodetection by subcutaneous or systemic injection.
    Ann Surg. 1986 Sep;204(3):223-35 PMID: 3753057
  33. A rapid method for the determination of human CEA/mouse anti-CEA immune complexes in patients undergoing immunoscintigraphy.
    Eur J Nucl Med. 1989;15(6):321-5 PMID: 2767081
  34. Tumor location detected with radioactively labeled monoclonal antibody and external scintigraphy.
    Science. 1979 Nov 16;206(4420):844-7 PMID: 493985
  35. Carcinoembryonic antigen in the management of colorectal cancer.
    Acta Hepatogastroenterol (Stuttg). 1979 Feb;26(1):1-3 PMID: 425796
  36. Advances in 99mTc-labeling of antibodies.
    Nuklearmedizin. 1987 Feb;26(1):7-12 PMID: 3588319
  37. Human biodistribution of 111In-labeled B72.3 monoclonal antibody.
    Cancer Res. 1990 Feb 1;50(3 Suppl):932s-936s PMID: 2297744
  38. Clinical studies of cancer radioimmunodetection with carcinoembryonic antigen monoclonal antibody fragments labeled with 123I or 99mTc.
    Cancer Res. 1990 Feb 1;50(3 Suppl):909s-921s PMID: 2297741
  39. Clinical parameters related to optimal tumor localization of indium-111-labeled mouse antimelanoma monoclonal antibody ZME-018.
    J Nucl Med. 1987 Jan;28(1):25-33 PMID: 3794809
  40. Development of a stable radioiodinating reagent to label monoclonal antibodies for radiotherapy of cancer.
    J Nucl Med. 1989 Feb;30(2):216-26 PMID: 2738650
  41. DEMONSTRATION OF TUMOR-SPECIFIC ANTIGENS IN HUMAN COLONIC CARCINOMATA BY IMMUNOLOGICAL TOLERANCE AND ABSORPTION TECHNIQUES.
    J Exp Med. 1965 Mar 1;121:439-62 PMID: 14270243
  42. Differential response of normal and tumor microcirculation to hyperthermia.
    Cancer Res. 1984 Feb;44(2):605-12 PMID: 6692365
  43. Interferon-induced changes in pharmacokinetics and tumor uptake of 111In-labeled antimelanoma antibody 96.5 in melanoma patients.
    J Natl Cancer Inst. 1988 Apr 6;80(3):160-5 PMID: 3346909
  44. The development and use of radiolabeled antitumor antibodies.
    Cancer Res. 1980 Aug;40(8 Pt 2):2960-4 PMID: 6994879
  45. Human immunological response to mouse monoclonal antibodies in the treatment or diagnosis of malignant diseases.
    Nucl Med Commun. 1988 Nov;9(11):919-30 PMID: 3075018
  46. Technetium-99m labeling of murine monoclonal antibody fragments.
    J Nucl Med. 1986 May;27(5):685-93 PMID: 3086522
  47. Studies on the exchange of fluids between host and tumor. II. The blood flow of hepatomas and other tumors in rats and mice.
    J Natl Cancer Inst. 1961 Dec;27:1465-91 PMID: 13902916
  48. A new method for 99Tcm-labelling of proteins with an application to clot detection with an antifibrin monoclonal antibody.
    Nucl Med Commun. 1987 Oct;8(10):771-7 PMID: 3431759
  49. The labeling of DTPA-coupled proteins with 99mTc.
    Int J Appl Radiat Isot. 1984 Jul;35(7):617-21 PMID: 6469392
  50. Clinical radioimmunodetection of cancer with radioactive antibodies to human chorionic gonadotropin.
    Science. 1980 Jun 13;208(4449):1284-6 PMID: 7375942
  51. Radioimmunoscintigraphy with 111In labelled monoclonal antibody fragments (F(ab')2 BW 431/31) against CEA: radiolabelling, antibody kinetics and distribution, findings in tumour and non-tumour patients.
    Nucl Med Commun. 1989 Sep;10(9):627-41 PMID: 2616103
  52. Radioimmunodetection of melanoma utilizing In-111 96.5 monoclonal antibody: a preliminary report.
    Radiology. 1985 May;155(2):493-9 PMID: 3983401
  53. The limitations of the dual radionuclide subtraction technique for the external detection of tumours by radioiodine-labelled antibodies.
    Br J Radiol. 1983 Feb;56(662):101-8 PMID: 6297651
  54. Radioimmunodetection of cancer with radioactive antibodies to carcinoembryonic antigen.
    Cancer Res. 1980 Aug;40(8 Pt 2):2984-92 PMID: 7397693
  55. Radioimmunodetection of human tumor xenografts by monoclonal antibodies.
    Cancer Res. 1983 Jun;43(6):2731-5 PMID: 6342757
  56. Use of specific antibody for rapid clearance of circulating blood background from radiolabeled tumor imaging proteins.
    Eur J Nucl Med. 1984;9(5):209-15 PMID: 6428891
  57. Mouse/human chimeric antibodies to a tumor-associated antigen: biologic activity of the four human IgG subclasses.
    J Natl Cancer Inst. 1988 Dec 7;80(19):1553-9 PMID: 3143014
  58. Physiological barriers to delivery of monoclonal antibodies and other macromolecules in tumors.
    Cancer Res. 1990 Feb 1;50(3 Suppl):814s-819s PMID: 2404582
  59. Complementation of intracavitary and intravenous administration of a monoclonal antibody (B72.3) in patients with carcinoma.
    Cancer Res. 1987 Aug 1;47(15):4218-24 PMID: 3607761
  60. Antibody-guided localization of intraperitoneal tumors following intraperitoneal or intravenous antibody administration.
    Cancer Res. 1987 Dec 15;47(24 Pt 1):6528-31 PMID: 3677091
  61. Radiolabelled monoclonal antibodies for the detection of cancer.
    Am J Physiol Imaging. 1986;1(1):44-53 PMID: 3330440
  62. New method for the chelation of indium-111 to monoclonal antibodies: biodistribution and imaging of athymic mice bearing human colon carcinoma xenografts.
    J Nucl Med. 1987 May;28(5):861-70 PMID: 3106595
  63. Targeting of cancer with radiolabeled antibodies. Prospects for imaging and therapy.
    Arch Pathol Lab Med. 1988 Jun;112(6):580-7 PMID: 3288167
  64. Imaging approach in radioimmunodetection.
    Cancer Res. 1980 Aug;40(8 Pt 2):3046-9 PMID: 7397699
  65. Radiation enhancement of radiolabelled antibody deposition in tumors.
    Int J Radiat Oncol Biol Phys. 1987 Dec;13(12):1839-44 PMID: 3679921
  66. Immunoscintigraphy for detection of lymph node metastases from breast cancer.
    Lancet. 1984 Dec 1;2(8414):1245-7 PMID: 6150280
  67. Specific and stable labeling of antibodies with technetium-99m with a diamide dithiolate chelating agent.
    Proc Natl Acad Sci U S A. 1988 Jun;85(11):4025-9 PMID: 3375252
  68. Innovations that influence the pharmacology of monoclonal antibody guided tumor targeting.
    Cancer Res. 1990 Feb 1;50(3 Suppl):820s-827s PMID: 1688734
  69. Localization of the monoclonal antibody HMFG2 after intravenous and intraperitoneal injection into nude mice bearing subcutaneous and intraperitoneal human ovarian cancer xenografts.
    Cancer Res. 1987 Sep 1;47(17):4714-8 PMID: 3621167
  70. Macroscopic dosimetry for radioimmunotherapy: nonuniform activity distributions in solid tumors.
    Med Phys. 1989 Jan-Feb;16(1):66-74 PMID: 2921982
  71. Carcinoembryonic antigen present in human colonic neoplasms serially propagated in hamsters.
    Science. 1972 Mar 10;175(4026):1117-8 PMID: 5060045
  72. Quantitative analyses of selective radiolabeled monoclonal antibody localization in metastatic lesions of colorectal cancer patients.
    Cancer Res. 1987 Feb 15;47(4):1185-9 PMID: 3802099
  73. [Critical oxygen and glucose supply of malignant tumors].
    Dtsch Med Wochenschr. 1976 Dec 3;101(49):1810-6 PMID: 1001189
  74. Influence of circulating antigen on the biodistribution and tumour localization of radiolabelled monoclonal antibody in a human tumour: nude mouse xenograft model.
    Eur J Cancer Clin Oncol. 1989 Sep;25(9):1325-32 PMID: 2806356
  75. Intraperitoneal radio-localization of tumors pre-targeted by biotinylated monoclonal antibodies.
    Int J Cancer. 1990 Jun 15;45(6):1184-9 PMID: 2351490
  76. Pharmacokinetics of 111In-labeled OC-125 antibody in cancer patients compared with the 19-9 antibody.
    Cancer Res. 1987 Nov 15;47(22):6111-7 PMID: 3664510
  77. Radiolabelled monoclonal antibodies: a new diagnostic tool in nuclear medicine.
    Radiother Oncol. 1984 Mar;1(4):333-8 PMID: 6334332
  78. Clinical studies on the radioimmunodetection of tumors containing alpha-fetoprotein.
    Cancer. 1980 May 15;45(10):2500-5 PMID: 6155193
  79. Site-specifically modified 111In labelled antibodies give low liver backgrounds and improved radioimmunoscintigraphy.
    Int J Rad Appl Instrum B. 1986;13(4):347-52 PMID: 3793488
  80. Future role of radiolabeled monoclonal antibodies in oncological diagnosis and therapy.
    Semin Nucl Med. 1989 Oct;19(4):332-9 PMID: 2678484
  81. Recent developments in the radiolabeling of antibodies with iodine, indium, and technetium.
    Semin Nucl Med. 1990 Jan;20(1):80-91 PMID: 2404343
  82. Protein and cell membrane iodinations with a sparingly soluble chloroamide, 1,3,4,6-tetrachloro-3a,6a-diphrenylglycoluril.
    Biochem Biophys Res Commun. 1978 Feb 28;80(4):849-57 PMID: 637870
  83. Multicompartmental analysis of the kinetics of radioiodinated monoclonal antibody in patients with cancer.
    J Nucl Med. 1986 Aug;27(8):1243-54 PMID: 3488377
  84. An enzymic method for the trace iodination of immunoglobulins and other proteins.
    Biochem J. 1969 Jun;113(2):299-305 PMID: 4185494
  85. Human anti-idiotype antibodies in cancer patients: Is the modulation of the immune response beneficial for the patient?
    Proc Natl Acad Sci U S A. 1984 Jan;81(1):216-9 PMID: 6582477
  86. Localisation of malignant germ-cell tumours by external scanning after injection of radiolabelled anti-alpha-fetoprotein.
    Br Med J (Clin Res Ed). 1981 Oct 10;283(6297):942-4 PMID: 6169388
  87. Recombinant interferon enhances monoclonal antibody-targeting of carcinoma lesions in vivo.
    Science. 1987 Feb 20;235(4791):895-8 PMID: 3580039
  88. Human immune response to multiple injections of murine monoclonal IgG.
    J Immunol. 1985 Aug;135(2):1530-5 PMID: 3874237
  89. Indium-111 T101 monoclonal antibody is superior to iodine-131 T101 in imaging of cutaneous T-cell lymphoma.
    J Nucl Med. 1987 Mar;28(3):281-7 PMID: 3102699
  90. Localization of mammary tumors in vivo with 131I-labeled Fab fragments of antibodies against mouse mammary epithelial (MME) antigens.
    Cancer. 1981 Oct 15;48(8):1768-75 PMID: 7284975
  91. Studies concerning the effect of external irradiation on localization of radiolabeled monoclonal antibody B72.3 to human colon carcinoma xenografts.
    Int J Radiat Oncol Biol Phys. 1989 Mar;16(3):721-9 PMID: 2921170
  92. Radiohalogenation of a monoclonal antibody using an N-succinimidyl 3-(tri-n-butylstannyl)benzoate intermediate.
    Cancer Res. 1988 Mar 15;48(6):1446-50 PMID: 3345515
  93. A perspective of monoclonal antibodies: past, present, and future.
    Semin Nucl Med. 1989 Jul;19(3):158-65 PMID: 2474854
  94. Comparison of tumor targeting of mouse monoclonal and goat polyclonal antibodies to carcinoembryonic antigen in the GW-39 human tumor-hamster host model.
    Cancer Res. 1988 Apr 1;48(7):1823-8 PMID: 3349460
  95. Biologic characterization of melanoma tumors by antigen-specific targeting of radiolabeled anti-tumor antibodies.
    J Nucl Med. 1991 Feb;32(2):287-91 PMID: 1992033
  96. The labeling of high affinity sites of antibodies with 99mTc.
    Int J Nucl Med Biol. 1985;12(1):3-8 PMID: 2989197
  97. Pharmacokinetics of 99mTc(Sn)- and 131I-labeled anti-carcinoembryonic antigen monoclonal antibody fragments in nude mice.
    Cancer Res. 1987 Mar 15;47(6):1691-4 PMID: 3815365
  98. Preparation of iodine-131 labelled human growth hormone of high specific activity.
    Nature. 1962 May 5;194:495-6 PMID: 14450081
  99. Preoperative imaging of colorectal carcinoma with 111In-labeled anticarcinoembryonic antigen monoclonal antibody.
    Cancer Res. 1986 Dec;46(12 Pt 1):6494-502 PMID: 3779657
  100. Transport of molecules across tumor vasculature.
    Cancer Metastasis Rev. 1987;6(4):559-93 PMID: 3327633
  101. Demonstration of antibodies against human malignant melanoma by immunofluorescence.
    Surgery. 1968 Jul;64(1):233-40 PMID: 4173159
  102. Localization of I-131-labeled goat and primate anti-carcinoembryonic antigen(CEA) antibodies in patients with cancer.
    Invest Radiol. 1982 Jul-Aug;17(4):350-5 PMID: 6752092
  103. Radioimmunoimaging in malignant melanoma with 111In-labeled monoclonal antibody 96.5.
    Cancer Res. 1985 May;45(5):2376-81 PMID: 3986779
  104. Use of radiolabelled monoclonal anti-CEA antibodies for the detection of human carcinomas by external photoscanning and tomoscintigraphy.
    Immunol Today. 1981 Dec;2(12):239-49 PMID: 25290651
  105. Metabolizable 111In chelate conjugated anti-idiotype monoclonal antibody for radioimmunodetection of lymphoma in mice.
    Eur J Nucl Med. 1986;12(9):455-60 PMID: 3102237
  106. Quantitative analysis of melanoma-associated antigen p97 in normal and neoplastic tissues.
    Proc Natl Acad Sci U S A. 1981 Jan;78(1):539-43 PMID: 6165996
  107. Pharmacokinetics and antibodies.
    J Nucl Med. 1987 Aug;28(8):1358-62 PMID: 3612296
  108. Improved tumor localization with increasing dose of indium-111-labeled anti-carcinoembryonic antigen monoclonal antibody ZCE-025 in metastatic colorectal cancer.
    J Clin Oncol. 1988 Aug;6(8):1220-30 PMID: 3045263
  109. Immunolymphoscintigraphy and the dose dependence of 111In-labeled T101 monoclonal antibody in patients with cutaneous T-cell lymphoma.
    Cancer Res. 1987 Nov 15;47(22):6093-9 PMID: 3499222
  110. Enhancement of monoclonal antibody binding to melanoma with single dose radiation or hyperthermia.
    NCI Monogr. 1987;(3):47-52 PMID: 3821918
  111. Phase 1 immunolymphoscintigraphy with an In-111-labeled antimelanoma monoclonal antibody.
    Radiology. 1986 Nov;161(2):419-22 PMID: 3763912
  112. Experimental radiation therapy of tumors with I-131-carrying antibodies to fibrin.
    Cancer Res. 1960 Nov;20:1488-94 PMID: 13686301
  113. Localization of 131I-labeled p97-specific Fab fragments in human melanoma as a basis for radiotherapy.
    J Clin Invest. 1983 Dec;72(6):2101-14 PMID: 6196380
  114. Monoclonal antibodies.
    Sci Am. 1980 Oct;243(4):66-74 PMID: 6158758
  115. The effect of certain variables on the tumor and tissue distribution of tracers. Part 1; Carrier.
    Invest Radiol. 1979 Nov-Dec;14(6):482-92 PMID: 528167
  116. Detection of tumours using radiolabelled antibodies.
    Radiography. 1983 Jan;49(577):5-12 PMID: 6191357
  117. Development of radiochemically pure antibodies.
    Cancer Res. 1990 Feb 1;50(3 Suppl):780s-782s PMID: 2297723
  118. Investigations of avidin and biotin for imaging applications.
    J Nucl Med. 1987 Aug;28(8):1294-302 PMID: 3612292
Article Info
Journal
Journal of cancer research and clinical oncology
Abbr.
J Cancer Res Clin Oncol
ISSN
0171-5216
DOI
10.1007/BF01192305
Published
1992-00-00
Pages
1-15
Language
English
Region
Germany
NLM ID
7902060
Subset
IM
External Links
PubMed source DOI: 10.1007/BF01192305 View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2