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PMID: 17274084 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution.

Angewandte Chemie (International ed. in English) ·Vol. 46 ·No. 11 ·2007-00-00 ·Pages 1864-8

Reese M, Sánchez-Pedregal VM, Kubicek K, Meiler J, Blommers MJ, Griesinger C, Carlomagno T

Abstract

暂无摘要

MeSH Terms

Antineoplastic Agents/chemistry Epothilones/chemistry Magnesium/chemistry Magnetic Resonance Spectroscopy Microtubules/chemistry,drug effects,genetics Models, Molecular Solutions Structure-Activity Relationship Tubulin/chemistry,genetics

Chemicals

Antineoplastic Agents Epothilones Solutions Tubulin epothilone A Magnesium

Authors & Affiliations

7 authors, click to expand affiliations / ORCID

Reese Marcel

Abteilung für NMR-basierte Strukturbiologie, Max-Planck-Institut für Biophysikalische Chemie, Am Fassberg 11, 37077 Göttingen, Germany.

Sánchez-Pedregal Víctor M

Kubicek Karel

Meiler Jens

Blommers Marcel J J

Griesinger Christian

Carlomagno Teresa

Article Info

Journal

Angewandte Chemie (International ed. in English)

Abbr.

Angew Chem Int Ed Engl

ISSN

1433-7851

DOI

10.1002/anie.200604505

Published

2007-00-00

Pages

1864-8

Language

English

Region

Germany

NLM ID

0370543

Subset

External Links

PubMed source DOI: 10.1002/anie.200604505 View journal details

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Structural basis of the activity of the microtubule-stabilizing agent epothilone a studied by NMR spectroscopy in solution.

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