Induction of Mutations by gamma-Rays in Pregonial Germ Cells of Zebrafish Embryos.

Genetics ·Vol. 103 ·No. 1 ·1983-01-00 ·Pages 125-36

Walker C, Streisinger G

Abstract

Specific locus (gol-1) germ line mutations are induced by gamma-rays with high frequencies (about 10(-5) r( -1)) during cleavage divisions in zebrafish. Mutant clone sizes range from 3 to 50% of the total number of germ cells, with a mean of about 10%, when embryos are exposed between the 16 and 10(3) cell stages. About five pregonial cells are calculated to be present during the cleavage period.

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Walker C

Institute of Molecular Biology, University of Oregon, Eugene, Oregon 97403.

Streisinger G

References (5)

5 references, click to expand

Evidence from mutable genes concerning the origin of the germ line.
Basic Life Sci. 1978;12:209-24 PMID: 752319
Definition of functional units in a small chromosomal segment of the mouse and its use in interpreting the nature of radiation-induced mutations.
Mutat Res. 1971 Jan;11(1):107-23 PMID: 5556347
Frequency of gamma-Ray Induced Specific Locus and Recessive Lethal Mutations in Mature Germ Cells of the Zebrafish, BRACHYDANIO RERIO.
Genetics. 1983 Jan;103(1):109-23 PMID: 17246098
Production of clones of homozygous diploid zebra fish (Brachydanio rerio).
Nature. 1981 May 28;291(5813):293-6 PMID: 7248006
Further evidence demonstrating germinal selection in early premeiotic germ cells of Drosophila males.
Genetics. 1966 Aug;54(2):687-96 PMID: 5968648

Article Info

Journal

Genetics

Abbr.

Genetics

ISSN

0016-6731

DOI

10.1093/genetics/103.1.125

Published

1983-01-00

Pages

125-36

Language

English

Region

United States

NLM ID

0374636

PMCID

PMC1202017

External Links

PubMed source DOI: 10.1093/genetics/103.1.125 PMC Full Text View journal details

Analysis Services

Induction of Mutations by gamma-Rays in Pregonial Germ Cells of Zebrafish Embryos.

Contact

WeChat Official Account