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PMID: 1723739 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

Bacterial endotoxin: molecular relationships between structure and activity.

Infectious disease clinics of North America ·Vol. 5 ·No. 4 ·1991-12-00 ·Pages 753-79

Rietschel ET, Seydel U, Zähringer U, Schade UF, Brade L, Loppnow H, Feist W, Wang MH, Ulmer AJ, Flad HD

Abstract

The significance of endotoxins in bacterial infection and their role as bacterial surface antigens (O antigens) have stimulated investigations into their chemical nature and the mechanisms of their biologic action during the last few decades. This article summarizes some of the recent results and emphasizes structure-activity relationships.

MeSH Terms

Animals Antibodies, Bacterial/immunology Carbohydrate Sequence Endotoxins/chemistry,immunology Epitopes Gram-Negative Bacteria/chemistry,immunology Humans Immune System Lipopolysaccharides/chemistry,immunology Molecular Sequence Data Molecular Structure Structure-Activity Relationship

Chemicals

Antibodies, Bacterial Endotoxins Epitopes Lipopolysaccharides

Authors & Affiliations

10 authors, click to expand affiliations / ORCID

Rietschel E T

Forschungsinstitut Borstel, Institut für Experimentelle Biologie und Medizin, Germany.

Seydel U

Zähringer U

Schade U F

Brade L

Loppnow H

Feist W

Wang M H

Ulmer A J

Flad H D

Article Info

Journal

Infectious disease clinics of North America

Abbr.

Infect Dis Clin North Am

ISSN

0891-5520

Published

1991-12-00

Pages

753-79

Language

English

Region

United States

NLM ID

8804508

Subset

External Links

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