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PMID: 17199027 Published · ppublish English Journal Article Review

Talampanel.

Howes JF, Bell C

Abstract

Talampanel is a novel anticonvulsant that acts as an allosteric inhibitor of the AMPA receptor. Talampanel has a broad spectrum of action in animal models of epilepsy and neuroprotection. Clinical experience to date has been able to show effectiveness in reduction of seizures in patients with refractory partial seizures.

MeSH Terms
Animals Antineoplastic Agents Benzodiazepines Brain/drug effects Clinical Trials as Topic Epilepsy/drug therapy Humans
Chemicals
Antineoplastic Agents Benzodiazepines talampanel
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Howes John F
Department of New Drug Development, IVAX Research, Inc., Miami, Florida 33137, USA.
Bell Cynthia
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21 references, click to expand
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Article Info
Journal
Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics
Abbr.
Neurotherapeutics
ISSN
1933-7213
Published
2007-01-00
Pages
126-9
Language
English
Region
United States
NLM ID
101290381
PMCID
PMC7479696
Subset
IM
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