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PMID: 17186018 Published · ppublish English Review

The Connectivity Map: a new tool for biomedical research.

Nature reviews. Cancer ·Vol. 7 ·No. 1 ·2007-00-00 ·Pages 54-60

Lamb J

Abstract

The ultimate objective of biomedical research is to connect human diseases with the genes that underlie them and drugs that treat them. But this remains a daunting task, and even the most inspired researchers still have to resort to laborious screens of genetic or chemical libraries. What if at least some parts of this screening process could be systematized and centralized? And hits found and hypotheses generated with something resembling an internet search engine? These are the questions the Connectivity Map project set out to answer.

MeSH Terms
Algorithms Animals Biomedical Research Computational Biology/methods Gene Expression Regulation Genome Humans Information Services Information Storage and Retrieval Models, Biological Models, Genetic Neoplasms/genetics Phenotype Software
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Lamb Justin
Broad Institute of the Massachusetts Institute of Technology and Harvard University, Cambridge, Massachusetts 02142, USA. justin@broad.mit.edu
Article Info
Journal
Nature reviews. Cancer
Abbr.
Nat Rev Cancer
ISSN
1474-175X
Published
2007-00-00
Pages
54-60
Language
English
Region
England
NLM ID
101124168
Subset
IM
Analysis Services
Analysis Services

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