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PMID: 17146701 Published · ppublish English Journal Article Research Support, N.I.H., Extramural

The broad autism phenotype questionnaire.

Journal of autism and developmental disorders ·Vol. 37 ·No. 9 ·2007-10-00 ·Pages 1679-90

Hurley RS, Losh M, Parlier M, Reznick JS, Piven J

Abstract

The broad autism phenotype (BAP) is a set of personality and language characteristics that reflect the phenotypic expression of the genetic liability to autism, in non-autistic relatives of autistic individuals. These characteristics are milder but qualitatively similar to the defining features of autism. A new instrument designed to measure the BAP in adults, the Broad Autism Phenotype Questionnaire (BAPQ), was administered to 86 parents of autistic individuals and 64 community control parents. Sensitivity and specificity of the BAPQ for detecting the BAP were high (>70%). Parents of children with autism had significantly higher scores on all three subscales: aloof personality, rigid personality, and pragmatic language. This instrument provides a valid and efficient measure for characterizing the BAP.

MeSH Terms
Autistic Disorder/diagnosis Female Humans Male Middle Aged Phenotype Surveys and Questionnaires
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Hurley Robert S E
Department of Psychiatry, Neurodevelopmental Disorders Research Center, University of North Carolina, Chapel Hill, NC 27599-3366, USA.
Losh Molly
Parlier Morgan
Reznick J Steven
Piven Joseph
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Article Info
Journal
Journal of autism and developmental disorders
Abbr.
J Autism Dev Disord
ISSN
0162-3257
DOI
10.1007/s10803-006-0299-3
Published
2007-10-00
Epub
2006-00-05
Pages
1679-90
Language
English
Region
United States
NLM ID
7904301
Subset
IM
Grants
NICHD NIH HHS · P30 HD03110 · United States
NIMH NIH HHS · U54 MH66418-02 · United States
Corrections
CommentIn
PMID: 18726680
External Links
PubMed source DOI: 10.1007/s10803-006-0299-3 View journal details
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