Multipotent adult progenitor cell and stem cell plasticity.
作者:
Jahagirdar(Balkrishna N),Verfaillie(Catherine M)
状态:
发布时间2006-11-29
, 更新时间 2009-12-11
期刊:
Stem Cell Rev
摘要:
Stem cells are defined by their biological function. A stem cell is an undifferentiated cell that self-renews to maintain the stem cell pool and at the single-cell level differentiates into more than one mature, functional cell. In addition, when transplanted, a stem cell should be capable of replacing a damaged organ or tissue for the lifetime of the recipient. Some would argue that stem cells should also be capable of functionally integrating into nondamaged tissues. Stem cells are critical to both embryogenesis and postnatal life.