Another job for the talented p120-catenin.

Cell ·Vol. 127 ·No. 5 ·2006-12-01 ·Pages 875-7

Niessen CM, Yap AS

Abstract

Given the complexity of signaling pathways in the cell, it is a mystery how these pathways communicate with one other. In this issue of Cell, Wildenberg et al. (2006) reveal that the key effector molecule p120-catenin can mediate crosstalk between the Rac and Rho signaling pathways.

MeSH Terms

Adherens Junctions/metabolism Animals Catenins Cell Adhesion Cell Adhesion Molecules/deficiency,metabolism DNA-Binding Proteins/metabolism GTPase-Activating Proteins/metabolism Mice Phosphoproteins/deficiency,metabolism Repressor Proteins/metabolism rac GTP-Binding Proteins/metabolism rho GTP-Binding Proteins/antagonists & inhibitors,metabolism

Chemicals

Arhgap35 protein, mouse Catenins Cell Adhesion Molecules DNA-Binding Proteins GTPase-Activating Proteins Phosphoproteins Repressor Proteins delta catenin rac GTP-Binding Proteins rho GTP-Binding Proteins

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Niessen Carien M

Center for Molecular Medicine Cologne (CMMC), University of Cologne, Joseph Stelzmannstrasse 9, 50931 Cologne. carien.niessen@uni-koeln.de

Yap Alpha S

Article Info

Journal

Cell

Abbr.

Cell

ISSN

0092-8674

DOI

10.1016/j.cell.2006.11.014

carien.niessen@uni-koeln.de

Published

2006-12-01

Pages

875-7

Language

English

Region

United States

NLM ID

0413066

Subset

Corrections

CommentOn

PMID: 17129786

External Links

PubMed source DOI: 10.1016/j.cell.2006.11.014 View journal details

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Another job for the talented p120-catenin.

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