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PMID: 17043314 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Canalization of auxin flow by Aux/IAA-ARF-dependent feedback regulation of PIN polarity.

Genes & development ·Vol. 20 ·No. 20 ·2006-10-15 ·Pages 2902-11

Sauer M, Balla J, Luschnig C, Wisniewska J, Reinöhl V, Friml J, Benková E

Abstract

Plant development is characterized by a profound ability to regenerate and form tissues with new axes of polarity. An unsolved question concerns how the position within a tissue and cues from neighboring cells are integrated to specify the polarity of individual cells. The canalization hypothesis proposes a feedback effect of the phytohormone auxin on the directionality of intercellular auxin flow as a means to polarize tissues. Here we identify a cellular and molecular mechanism for canalization. Local auxin application, wounding, or auxin accumulation during de novo organ formation lead to rearrangements in the subcellular polar localization of PIN auxin transport components. This auxin effect on PIN polarity is cell-specific, does not depend on PIN transcription, and involves the Aux/IAA-ARF (indole-3-acetic acid-auxin response factor) signaling pathway. Our data suggest that auxin acts as polarizing cue, which links individual cell polarity with tissue and organ polarity through control of PIN polar targeting. This feedback regulation provides a conceptual framework for polarization during multiple regenerative and patterning processes in plants.

MeSH Terms
Arabidopsis/metabolism Arabidopsis Proteins/metabolism Gene Expression Regulation, Plant Indoleacetic Acids/chemistry,metabolism Peas Phototropism Plant Growth Regulators Plant Physiological Phenomena Plant Proteins/physiology Plant Roots/metabolism Signal Transduction Transcription, Genetic
Chemicals
Arabidopsis Proteins Indoleacetic Acids Plant Growth Regulators Plant Proteins indoleacetic acid
Authors & Affiliations
7 authors, click to expand affiliations / ORCID
Sauer Michael
Center for Plant Molecular Biology (ZMBP), University Tübingen, 72076 Tübingen, Germany.
Balla Jozef
Luschnig Christian
Wisniewska Justyna
Reinöhl Vilém
Friml Jirí
Benková Eva
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Article Info
Journal
Genes & development
Abbr.
Genes Dev
ISSN
0890-9369
DOI
10.1101/gad.390806
Published
2006-10-15
Pages
2902-11
Language
English
Region
United States
NLM ID
8711660
PMCID
PMC1619939
Subset
IM
Corrections
ErratumIn
-
External Links
PubMed source DOI: 10.1101/gad.390806 PMC Full Text View journal details
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