Gene Transcription in Trichomonas vaginalis.

Since the cloning of the first gene from the flagellated, parasitic protist Trichomonas vaginalis in 1990, at least a partial sequence has been obtained from over 100 genes. Molecular and biochemical analyses using these genes have enhanced our understanding of metabolism, organelle biogenesis, drug susceptibility, phylogeny and basic properties of transcription in trichomonads. Here, David Liston and Patricia Johnson discuss the available data on the regulation of transcription of protein-coding genes in T. vaginalis.