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PMID: 1699793 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Primary structure of cAMP-gated channel from bovine olfactory epithelium.

FEBS letters ·Vol. 270 ·No. 1-2 ·1990-09-17 ·Pages 24-9

Ludwig J, Margalit T, Eismann E, Lancet D, Kaupp UB

Abstract

The complete amino-acid sequence of the bovine olfactory epithelium adenosine 3',5'-cyclic monophosphate (cAMP)-gated channel has been determined by cloning and sequencing its cDNA. It exhibits a high degree of sequence homology with the cGMP-gated channel of rod photoreceptors, suggesting that cyclic nucleotide-gated channels fall into a new family of genetically related proteins.

MeSH Terms
Amino Acid Sequence Animals Base Sequence Cattle Cloning, Molecular Cyclic AMP/physiology Cyclic GMP/physiology Ion Channel Gating Ion Channels/chemistry,genetics Molecular Sequence Data Neurons/chemistry Olfactory Mucosa/chemistry Poly A/genetics RNA, Messenger/genetics Sequence Homology, Nucleic Acid
Chemicals
Ion Channels RNA, Messenger Poly A Cyclic AMP Cyclic GMP
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Ludwig J
Institut für Biologische Informationsverarbeitung, Forschungszentrum Jülich, FRG.
Margalit T
Eismann E
Lancet D
Kaupp U B
Article Info
Journal
FEBS letters
Abbr.
FEBS Lett
ISSN
0014-5793
Published
1990-09-17
Pages
24-9
Language
English
Region
England
NLM ID
0155157
Subset
IM
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