Abstract
The development of the Functional Genomics Investigation Ontology (FuGO) is a collaborative, international effort that will provide a resource for annotating functional genomics investigations, including the study design, protocols and instrumentation used, the data generated and the types of analysis performed on the data. FuGO will contain both terms that are universal to all functional genomics investigations and those that are domain specific. In this way, the ontology will serve as the "semantic glue" to provide a common understanding of data from across these disparate data sources. In addition, FuGO will reference out to existing mature ontologies to avoid the need to duplicate these resources, and will do so in such a way as to enable their ease of use in annotation. This project is in the early stages of development; the paper will describe efforts to initiate the project, the scope and organization of the project, the work accomplished to date, and the challenges encountered, as well as future plans.
MeSH Terms
Biomedical Research/organization & administration,standards
Genomics/organization & administration,standards
Terminology as Topic
Workforce
Authors & Affiliations
22 authors, click to expand affiliations / ORCID
Whetzel Patricia L
Center for Bioinformatics and Department of Genetics, University of Pennsylvania School of Medicine, Philadelphia, Pennsylvania 19104, USA. whetzel@pcbi.upenn.edu
Brinkman Ryan R
Causton Helen C
Fan Liju
Field Dawn
Fostel Jennifer
Fragoso Gilberto
Gray Tanya
Heiskanen Mervi
Hernandez-Boussard Tina
Morrison Norman
Parkinson Helen
Rocca-Serra Philippe
Sansone Susanna-Assunta
Schober Daniel
Smith Barry
Stevens Robert
Stoeckert Christian J
Taylor Chris
White Joe
Wood Andrew
FuGO Working Group
References (12)
12 references, click to expand
-
Concept of sample in OMICS technology.
OMICS. 2006 Summer;10(2):127-37
PMID: 16901217
-
The MGED Ontology: a resource for semantics-based description of microarray experiments.
Bioinformatics. 2006 Apr 1;22(7):866-73
PMID: 16428806
-
Relations in biomedical ontologies.
Genome Biol. 2005;6(5):R46
PMID: 15892874
-
Protégé-2000: an open-source ontology-development and knowledge-acquisition environment.
AMIA Annu Symp Proc. 2003;:953
PMID: 14728458
-
Gene ontology: tool for the unification of biology. The Gene Ontology Consortium.
Nat Genet. 2000 May;25(1):25-9
PMID: 10802651
-
Generation Challenge Programme (GCP): standards for crop data.
OMICS. 2006 Summer;10(2):215-9
PMID: 16901229
-
Data standards for flow cytometry.
OMICS. 2006 Summer;10(2):209-14
PMID: 16901228
-
National Center for Biomedical Ontology: advancing biomedicine through structured organization of scientific knowledge.
OMICS. 2006 Summer;10(2):185-98
PMID: 16901225
-
A strategy capitalizing on synergies: the Reporting Structure for Biological Investigation (RSBI) working group.
OMICS. 2006 Summer;10(2):164-71
PMID: 16901222
-
Establishing reporting standards for metabolomic and metabonomic studies: a call for participation.
OMICS. 2006 Summer;10(2):158-63
PMID: 16901221
-
The work of the Human Proteome Organisation's Proteomics Standards Initiative (HUPO PSI).
OMICS. 2006 Summer;10(2):145-51
PMID: 16901219
-
MGED standards: work in progress.
OMICS. 2006 Summer;10(2):138-44
PMID: 16901218