Home LiteratureArticle Details
PMID: 1684510 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Research Support, U.S. Gov't, P.H.S. Review

Possible functions of tumor-associated carbohydrate antigens.

Current opinion in immunology ·Vol. 3 ·No. 5 ·1991-10-00 ·Pages 646-53

Hakomori S

Abstract

Expression of some tumor-associated carbohydrate antigens may define the stage, rate and phenotype of tumor progression and may have prognostic value. Some of these antigens are now recognized as adhesion molecules that define the site of metastasis. Monoclonal antibodies to tumor-associated carbohydrate antigens, or the antigens themselves, may serve not only as classic immunological reagents but also as anti-adhesion reagents for the prevention of tumor progression.

MeSH Terms
Amino Acid Sequence Animals Antibodies, Monoclonal/immunology Antigens, Neoplasm/physiology Carbohydrate Sequence Carbohydrates/immunology,physiology Cell Adhesion Cell Adhesion Molecules/physiology Gene Expression Regulation, Neoplastic Glycoproteins/immunology,physiology Humans Lewis Blood Group Antigens/immunology,physiology Lewis X Antigen/physiology Melanoma, Experimental/immunology,pathology Mice Molecular Sequence Data Neoplasm Invasiveness Neoplasm Metastasis Neoplasm Proteins/immunology,physiology Neoplasms/immunology,physiopathology Peptides/pharmacology Receptors, Immunologic/drug effects Receptors, Laminin Vaccination
Chemicals
Antibodies, Monoclonal Antigens, Neoplasm Carbohydrates Cell Adhesion Molecules Glycoproteins Lewis Blood Group Antigens Lewis X Antigen Neoplasm Proteins Peptides Receptors, Immunologic Receptors, Laminin
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Hakomori S
Biomembrane Institute, Seattle, Washington.
Article Info
Journal
Current opinion in immunology
Abbr.
Curr Opin Immunol
ISSN
0952-7915
DOI
10.1016/0952-7915(91)90091-e
Published
1991-10-00
Pages
646-53
Language
English
Region
England
NLM ID
8900118
Subset
IM
Grants
NCI NIH HHS · CA42505 · United States
External Links
PubMed source DOI: 10.1016/0952-7915(91)90091-e View journal details
Analysis Services
Analysis Services

Contact

No. 2 Wenbo Road, Zhangqiu District, Jinan, Shandong

Qilu Normal University · Genelibs Bioinformatics Lab

750 Shunhua Rd, Jinan

2F, Bldg F, University Science Park

Tel: 0531-88819269

WeChat Official Account

Follow our WeChat subscription account for real-time updates and the latest in medical and biological research.


Business Email

E-mail: product@genelibs.com

Copyright © 2026.Genelibs Jinan Honghui Biotechnology Co., Ltd. 鲁ICP备20007159号-2