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PMID: 16843042 Published · ppublish English Journal Article Review

Human cancer from environmental pollutants: the epidemiological evidence.

Mutation research ·Vol. 608 ·No. 2 ·2006-09-28 ·Pages 157-62

Boffetta P

Abstract

An increased risk of mesothelioma has been reported among individuals experiencing residential exposure to asbestos, while results for lung cancer are less consistent. Several studies have reported an increased risk of lung cancer risk from outdoor air pollution: on the basis of the results of the largest study, the proportion of lung cancers attributable to urban air pollution in Europe can be as high as 10.7%. A causal association has been established between second-hand tobacco smoking and lung cancer, which may be responsible for 1.6% of lung cancers. Radon is another carcinogen present in indoor air, which may be responsible for 4.5% of lung cancers. An increased risk of bladder might be due to water chlorination by-products. The available evidence on cancer risk following exposure to other environmental pollutants, including, pesticides, dioxins and electro-magnetic fields, is inconclusive.

MeSH Terms
Air Pollution, Indoor/adverse effects Arsenic/toxicity Asbestos/toxicity Dioxins/toxicity Electromagnetic Fields/adverse effects Environmental Pollutants/toxicity Europe/epidemiology Humans Neoplasms/chemically induced,epidemiology,etiology Pesticides/toxicity Radon/toxicity Risk Factors Tobacco Smoke Pollution/adverse effects Water Pollutants, Chemical/toxicity Water Purification
Chemicals
Dioxins Environmental Pollutants Pesticides Tobacco Smoke Pollution Water Pollutants, Chemical Asbestos Arsenic Radon
Authors & Affiliations
1 authors, click to expand affiliations / ORCID
Boffetta Paolo
International Agency for Research on Cancer, 150 cours Albert-Thomas, 69008 Lyon, France. boffetta@iarc.fr
Article Info
Journal
Mutation research
Abbr.
Mutat Res
ISSN
0027-5107
Published
2006-09-28
Epub
2006-00-13
Pages
157-62
Language
English
Region
Netherlands
NLM ID
0400763
Subset
IM
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