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PMID: 16732899 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't Review

RNA at the steering wheel.

Genome biology ·Vol. 7 ·No. 5 ·2006-00-00 ·Pages 218

Schmitt S, Paro R

Abstract

Expression of the genetic information encoded in our genomes is usually regulated by proteins interacting with the DNA. In some cases, however, noncoding RNAs transcribed from DNA control elements cooperate with histone-modifying enzymes to regulate gene expression, as has recently been shown for noncoding RNA originating from Polycomb- and Trithorax-group response elements.

MeSH Terms
Animals DNA-Binding Proteins/metabolism Drosophila Proteins/genetics,metabolism Drosophila melanogaster/genetics,metabolism Female Gene Expression Regulation Histone Methyltransferases Histone-Lysine N-Methyltransferase/metabolism Homeodomain Proteins/genetics Male Polycomb Repressive Complex 1 Protein Methyltransferases RNA, Untranslated/biosynthesis,genetics,physiology Regulatory Elements, Transcriptional Transcription Factors/genetics,metabolism
Chemicals
ASH1 protein, Drosophila DNA-Binding Proteins Drosophila Proteins Homeodomain Proteins Pc protein, Drosophila RNA, Untranslated Transcription Factors Ubx protein, Drosophila Histone Methyltransferases Protein Methyltransferases Histone-Lysine N-Methyltransferase Polycomb Repressive Complex 1
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Schmitt Sabine
Zentrum für Molekulare Biologie Heidelberg (ZMBH), University of Heidelberg, Im Neuenheimer Feld 282, 69120 Heidelberg, Germany.
Paro Renato
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19 references, click to expand
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Article Info
Journal
Genome biology
Abbr.
Genome Biol
ISSN
1474-760X
DOI
10.1186/gb-2006-7-5-218
Published
2006-00-00
Epub
2006-00-26
Pages
218
Language
English
Region
England
NLM ID
100960660
PMCID
PMC1779528
Subset
IM
External Links
PubMed source DOI: 10.1186/gb-2006-7-5-218 PMC Full Text View journal details
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