[The prognostic model--an aid for decision-making in the use of adjuvant cytostatic therapy in breast cancer].

The prognostic model as a help in deciding for the application of the adjuvant cytostatic therapy (ACT) in breast cancer is proposed. Risk factors including size of tumour, status of axial, value of hormonal receptors, grade of differentiation of tumour and age are included in the prognostic model. The clinical study comprises patients with breast cancer in premenopausal age with (30 patients) and without ACT (36). By using a multiple regression method and correlation analysis (multivariate analysis), the "weight"--the values of each risk factor have been determined in relation to the disease free interval and survival are obtained by employing the proposed prognostic model. By simple mathematical methods type of therapy is determined by the prognosis. This is the proposed model: Y = beta 0 + beta 1 x x1 + beta 2 x x2 + ... + beta k x xk. Coefficient values for each risk factor have been obtained by this clinical study. Full attention is not paid to the results of the ACT application in this presentation.