Glutathione causes a massive and selective induction of plant defense genes.

Plant physiology ·Vol. 87 ·No. 1 ·1988-05-00 ·Pages 206-10

Wingate VP, Lawton MA, Lamb CJ

Abstract

The reduced form of glutathione (GSH), when supplied to suspension cultured cells of bean (Phaseolus vulgaris L.) at concentrations in the range 0.01 to 1.0 millimolar, stimulates transcription of defense genes including those that encode cell wall hydroxyproline-rich glycoproteins and the phenylpropanoid biosynthetic enzymes phenylalanine ammonialyase (PAL) and chalcone synthase (CHS) involved in lignin (PAL) and phytoalexin (PAL, CHS) production. Transcriptional activation of these genes leads to marked accumulation of the corresponding transcripts, contributing to a massive change in the overall pattern of protein synthesis which closely resembles that previously observed in response to fungal elicitor. GSH causes a marked increase in extractable PAL activity, whereas the oxidized form of glutathione, constituent amino acids, or other reducing agents are inactive. Possible roles of GSH in signaling biological stress are discussed.

Authors & Affiliations

3 authors, click to expand affiliations / ORCID

Wingate V P

Plant Biology Laboratory, Salk Institute for Biological Studies, P.O. Box 85800, San Diego, California 92138-9216.

Lawton M A

Lamb C J

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Article Info

Journal

Plant physiology

Abbr.

Plant Physiol

ISSN

0032-0889

DOI

10.1104/pp.87.1.206

Published

1988-05-00

Pages

206-10

Language

English

Region

United States

NLM ID

0401224

PMCID

PMC1054726

External Links

PubMed source DOI: 10.1104/pp.87.1.206 PMC Full Text View journal details

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Glutathione causes a massive and selective induction of plant defense genes.

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