Nucleolar dominance in polytene cells of Drosophila.

Proceedings of the National Academy of Sciences of the United States of America ·Vol. 80 ·No. 14 ·1983-07-00 ·Pages 4427-31

Endow SA

Abstract

Previous studies indicate that genes from only one of the cell's nucleolus organizers undergo multiple rounds of DNA replication in polytene cells of Drosophila. This report presents evidence that this effect is mediated by a function that is associated with the ribosomal genes of the dominant or replicating X chromosome. This function can act in trans to result in replication of the ribosomal genes on the recessive X chromosome in flies that are bobbed for the dominant X chromosome. In these cases, ribosomal genes from both chromosomes undergo polytenization. Heterochromatic regions that flank the nucleolus organizer have little or no effect on nucleolar dominance. In addition, deletion of the compensatory response (cr(+)) locus does not affect the dominance, suggesting that ribosomal gene compensation and nucleolar dominance in polytene cells of Drosophila are separate genetic phenomena.

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Endow S A

Department of Microbiology and Immunology, Duke University Medical Center, Durham, North Carolina 27710.

References (14)

14 references, click to expand

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Article Info

Journal

Proceedings of the National Academy of Sciences of the United States of America

Abbr.

Proc Natl Acad Sci U S A

ISSN

0027-8424

DOI

10.1073/pnas.80.14.4427

Published

1983-07-00

Pages

4427-31

Language

English

Region

United States

NLM ID

7505876

PMCID

PMC384051

External Links

PubMed source DOI: 10.1073/pnas.80.14.4427 PMC Full Text View journal details

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Nucleolar dominance in polytene cells of Drosophila.

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