The Antennapedia gene is required and expressed in parasegments 4 and 5 of the Drosophila embryo.

The EMBO journal ·Vol. 5 ·No. 1 ·1986-01-00 ·Pages 135-141

Martinez-Arias A

Abstract

Transcripts homologous to the 5' exon of the Antp gene accumulate in parasegments 4 and 5 of the Drosophila embryo, where analysis of the cuticular phenotype of Antennapedia (Antp) embryos shows that there is a genetic requirement for the Antp gene. The pattern of Antp expression is different in different germ layers; the mesoderm expresses Antp only in parasegment 5; in the developing nervous system and the epidermis the pattern of expression is complex and suggests that interactions between different selector genes take place during wild-type development. Both genetic requirements and gene expression indicate that Antennapedia is the main morphological determinant in parasegment 4; in parasegment 5 it probably acts in concert with other selector genes.

Authors & Affiliations

1 authors, click to expand affiliations / ORCID

Martinez-Arias Alfonso

Medical Research Council, Laboratory of Molecular Biology, Hills Road, Cambridge CB2 2QH, UK.

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Article Info

Journal

The EMBO journal

Abbr.

EMBO J

ISSN

1460-2075

Published

1986-01-00

Pages

135-141

Language

English

Region

England

NLM ID

8208664

PMCID

PMC1166705

External Links

PubMed source PMC Full Text View journal details

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The Antennapedia gene is required and expressed in parasegments 4 and 5 of the Drosophila embryo.

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