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PMID: 164435 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S. Research Support, U.S. Gov't, P.H.S.

Deletion of the Escherichia coli crp gene.

Journal of bacteriology ·Vol. 122 ·No. 1 ·1975-04-00 ·Pages 338-40

Sabourin D, Beckwith J

Abstract

Spontaneous crp mutants Escherichia coli were selected from a strain that does not require 3',5'-cyclic adenosine monophosphate for CAP activity. Several deletions of the crp gene were characterized. The crp gene was not essential for growth of E. coli. crp mutations reduced the donor ability of Hfr strains.

MeSH Terms

Adenylyl Cyclases/biosynthesis Bacterial Proteins/biosynthesis Carbon/metabolism Chromosome Mapping Cyclic AMP/metabolism Escherichia coli/enzymology,growth & development,metabolism Genes Mutagens Mutation Nitrosoguanidines Recombination, Genetic Transduction, Genetic

Chemicals

Bacterial Proteins Mutagens Nitrosoguanidines Carbon Cyclic AMP Adenylyl Cyclases

Authors & Affiliations

2 authors, click to expand affiliations / ORCID

Sabourin D

Beckwith J

References (8)

8 references, click to expand

Pleiotropic deficiency of carbohydrate utilization in an adenyl cyclase deficient mutant of Escherichia coli.
Biochem Biophys Res Commun. 1969 Sep 24;37(1):151-7 PMID: 4310317
Cyclic AMP receptor protein of E. coli: its role in the synthesis of inducible enzymes.
Proc Natl Acad Sci U S A. 1970 Jun;66(2):480-7 PMID: 4317918
Mechanism of activation of catabolite-sensitive genes: a positive control system.
Proc Natl Acad Sci U S A. 1970 May;66(1):104-10 PMID: 4320461
Regulation of lac mRNA synthesis in a soluble cell-free system.
Nat New Biol. 1971 Mar 10;230(10):37-40 PMID: 4324112
Mechanism of initiation and repression of in vitro transcription of the lac operon of Escherichia coli.
Proc Natl Acad Sci U S A. 1971 Aug;68(8):1828-32 PMID: 4331560
Genetic characterization of mutations which affect catabolite-sensitive operons in Escherichia coli, including deletions of the gene for adenyl cyclase.
J Bacteriol. 1973 Nov;116(2):582-7 PMID: 4583241
Transposition of the Lac region of E. coli.
Cold Spring Harb Symp Quant Biol. 1966;31:393-401 PMID: 4866389
Allelic amber and ochre suppressors.
J Mol Biol. 1968 Sep 14;36(2):209-18 PMID: 5760539

Article Info

Journal

Journal of bacteriology

Abbr.

J Bacteriol

ISSN

0021-9193

DOI

10.1128/jb.122.1.338-340.1975

Published

1975-04-00

Pages

338-40

Language

English

Region

United States

NLM ID

2985120R

PMCID

PMC235677

Subset

External Links

PubMed source DOI: 10.1128/jb.122.1.338-340.1975 PMC Full Text View journal details

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Deletion of the Escherichia coli crp gene.

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