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PMID: 16381841 Published · ppublish English Journal Article Research Support, N.I.H., Extramural

TCDB: the Transporter Classification Database for membrane transport protein analyses and information.

Nucleic acids research ·Vol. 34 ·No. Database issue ·2006-01-01 ·Pages D181-6

Saier MH, Tran CV, Barabote RD

Abstract

The Transporter Classification Database (TCDB) is a web accessible, curated, relational database containing sequence, classification, structural, functional and evolutionary information about transport systems from a variety of living organisms. TCDB is a curated repository for factual information compiled from >10,000 references, encompassing approximately 3000 representative transporters and putative transporters, classified into >400 families. The transporter classification (TC) system is an International Union of Biochemistry and Molecular Biology approved system of nomenclature for transport protein classification. TCDB is freely accessible at http://www.tcdb.org. The web interface provides several different methods for accessing the data, including step-by-step access to hierarchical classification, direct search by sequence or TC number and full-text searching. The functional ontology that underlies the database structure facilitates powerful query searches that yield valuable data in a quick and easy way. The TCDB website also offers several tools specifically designed for analyzing the unique characteristics of transport proteins. TCDB not only provides curated information and a tool for classifying newly identified membrane proteins, but also serves as a genome transporter-annotation tool.

MeSH Terms
Databases, Protein Humans Internet Membrane Transport Proteins/chemistry,classification,physiology Sequence Analysis, Protein User-Computer Interface
Chemicals
Membrane Transport Proteins
Authors & Affiliations
3 authors, click to expand affiliations / ORCID
Saier Milton H
Division of Biological Sciences, University of California at San Diego, La Jolla, CA 92093-0116, USA. msaier@ucsd.edu
Tran Can V
Barabote Ravi D
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Article Info
Journal
Nucleic acids research
Abbr.
Nucleic Acids Res
ISSN
1362-4962
DOI
10.1093/nar/gkj001
Email
msaier@ucsd.edu
Published
2006-01-01
Pages
D181-6
Language
English
Region
England
NLM ID
0411011
PMCID
PMC1334385
Subset
IM
External Links
PubMed source DOI: 10.1093/nar/gkj001 PMC Full Text View journal details
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