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PMID: 163810 Published · ppublish English Journal Article Research Support, U.S. Gov't, Non-P.H.S.

Isolation of a metabolite capable of differentially supporting the growth of nicotinamide adenine dinucleotide auxotrophs of Escherichia coli.

Journal of bacteriology ·Vol. 121 ·No. 1 ·1975-01-00 ·Pages 212-8

Chen JL, Tritz GJ

Abstract

A compound, isolated from the culture fluid of a nadC auxotroph of Escherichia coli grown in a minimal medium, supports the growth of both a nadA and a nadB mutant. This metabolite exhibits an ultraviolet light absorption spectrum and a mass spectrum, different from quinolinic acid. This compound may be the precursor of quinolinic acid, an intermediate in the biosynthesis of nicotinamide adenosine dinucleotide.

MeSH Terms
Aspartic Acid/metabolism Escherichia coli/growth & development,metabolism Mutation NAD/metabolism Niacinamide/biosynthesis Nicotinic Acids/biosynthesis Quinolinic Acids
Chemicals
Nicotinic Acids Quinolinic Acids NAD Niacinamide Aspartic Acid
Authors & Affiliations
2 authors, click to expand affiliations / ORCID
Chen J L
Tritz G J
References (11)
11 references, click to expand
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Article Info
Journal
Journal of bacteriology
Abbr.
J Bacteriol
ISSN
0021-9193
DOI
10.1128/jb.121.1.212-218.1975
Published
1975-01-00
Pages
212-8
Language
English
Region
United States
NLM ID
2985120R
PMCID
PMC285633
Subset
IM
External Links
PubMed source DOI: 10.1128/jb.121.1.212-218.1975 PMC Full Text View journal details
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