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PMID: 16369040 Published · ppublish English Journal Article Research Support, Non-U.S. Gov't

Molecular characterization of the Escherichia coli asymptomatic bacteriuria strain 83972: the taming of a pathogen.

Infection and immunity ·Vol. 74 ·No. 1 ·2006-01-00 ·Pages 781-5

Klemm P, Roos V, Ulett GC, Svanborg C, Schembri MA

Abstract

Escherichia coli 83972 is a clinical asymptomatia bacteriuric isolate that is able to colonize the human urinary bladder without inducing an immune response. Here we demonstrate that one of the mechanisms by which this strain has become attenuated is through the mutation of its genes encoding type 1 and P fimbriae.

MeSH Terms
Amino Acid Sequence Bacteriuria/metabolism,microbiology Escherichia coli/genetics,pathogenicity,ultrastructure Escherichia coli Infections/metabolism,microbiology Fimbriae, Bacterial/genetics,ultrastructure Humans Molecular Sequence Data
Authors & Affiliations
5 authors, click to expand affiliations / ORCID
Klemm Per
School of Molecular and Microbial Sciences, Building 76, University of Queensland, Brisbane QLD 4072, Australia.
Roos Viktoria
Ulett Glen C
Svanborg Catharina
Schembri Mark A
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Article Info
Journal
Infection and immunity
Abbr.
Infect Immun
ISSN
0019-9567
DOI
10.1128/IAI.74.1.781-785.2006
Published
2006-01-00
Pages
781-5
Language
English
Region
United States
NLM ID
0246127
PMCID
PMC1346676
Subset
IM
External Links
PubMed source DOI: 10.1128/IAI.74.1.781-785.2006 PMC Full Text View journal details
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