HLA DQB1*0602 positive narcoleptic subjects with cataplexy have CSF lgG reactive to rat hypothalamic protein extract.

Adult Aged Animals Antibodies/immunology Cataplexy/genetics Enzyme-Linked Immunosorbent Assay Female HLA-DQ Antigens/genetics HLA-DQ beta-Chains Humans Hypothalamus/immunology,metabolism Immunoglobulin G/cerebrospinal fluid,immunology Male Membrane Glycoproteins/genetics Middle Aged Narcolepsy/cerebrospinal fluid,genetics,immunology Orexin Receptors Rats Receptors, G-Protein-Coupled Receptors, Neuropeptide/immunology,metabolism Sleep, REM/physiology

Antibodies HLA-DQ Antigens HLA-DQ beta-Chains HLA-DQB1 antigen Immunoglobulin G Membrane Glycoproteins Orexin Receptors Receptors, G-Protein-Coupled Receptors, Neuropeptide